Tissue engineering design of a synthetic liver scaffolds

Applications are invited for postgraduate research leading to a PhD degree in Biomedical Engineering within the subject area of Tissue Engineering.

Tissue engineering has shown great potential in the treatment of a large number of degenerative ailments, including osteoarthritis and cardiovascular disease, through the design of biological scaffolds.  Specifically, this approach can incorporate a biomaterial/scaffold that can provide suitable biomechanical and biocompatibility properties, and a favorable environment for cell attachment, cell growth and regeneration. Various scaffold types, including biodegradable polyesters and naturally derived extracellular matrix materials have been used with varying degrees of success in these areas over the past number of decades. 

This research focuses on the development of a synthetic based tissue engineered liver organelle scaffolds for the treatment of liver disease and failure.

The student will attain skills in biomaterial design, fabrication, characterisation and cell culture, using techniques such as; Scanning electron microscopy, Nano-indentation, fatigue testing, ELISA assays (biochemical content), real time-RT-PCR etc. These skills will be essential for a student perusing industrial careers in the biomedical sector; in addition they will be important for an academic career in Tissue Engineering/Biomedical Engineering.

Further Information: 

Principal Supervisor: 

Dr Anthony Callanan

Eligibility: 

To undertake this research, we are seeking a motivated candidate with an honours degree at 2:1 or above (or International equivalent) in any of these areas, chemical engineering, chemistry, materials science, physics, mechanical engineering, biomedical engineering, synthetic chemistry, organic chemistry, biochemistry, molecular biology or a cognate discipline.

Some knowledge and experience of material characterisation, cell culture, polymer chemistry, experimental work and an ability to work effectively as an independent researcher will be an advantage.

Further information on English language requirements for EU/Overseas applicants.

Funding: 

Possible funding and scholarship opportunities available – please enquire.

Open to students from the UK and EU.

Further information and other funding options.

Informal Enquiries: 

Closing Date: 

Friday, February 24, 2017