Transfection is a foundational technology in biosciences, biotechnology, and the development of biotherapeutic agents. Given its transcendence, it is problematic that transfection remains a poorly understood and insufficiently characterized endeavour. This PhD will dive deep into what parameters influence transfection and rework it as a fit-for-purpose technological foundation for the ambitions of those “engineering biology”. You’ll become expert in the genetic modification of mammalian cells (from lines to primary and stem cells) using a huge range of different transfection approaches and a host of analytical approaches from advanced imaging to biochemical assays and sequencing. Engineering Biology is developing rapidly as a preeminent technology for the delivery of much of humankind’s needs and this PhD will equip you to contribute to diverse fields from cultured meat to therapeutic cells. More background is available through reading this paper or contacting Prof. Alistair Elfick.
Further Information:
The University of Edinburgh is committed to equality of opportunity for all its staff and students, and promotes a culture of inclusivity. Please see details here: https://www.ed.ac.uk/equality-diversity
Closing Date:
Principal Supervisor:
Assistant Supervisor:
Dr Tom Robinson
Eligibility:
Minimum entry qualification - an Honours degree at 2:1 or above (or International equivalent) in a relevant science or engineering discipline, possibly supported by an MSc Degree. Further information on English language requirements for EU/Overseas applicants.
Funding:
Applications are welcomed from self-funded students, or students who are applying for scholarships from the University of Edinburgh or elsewhere.
