Deeply penetrating nanomedicine for breast cancer and metastasis

Cancers are leading causes of mortality in the world and tumour metastases are responsible for approximately 90% of all cancer-related deaths. Nanotechnology provides a robust platform to design and develop advanced drug delivery systems to improve therapeutics’ efficacy and diagnosis to treat breast cancer and metastasis. This project aims to develop nanomedicines with deep penetration to tumour and targeted delivery to metastasis to improve patient outcomes.

Our track record in this work:

  1. X Chen, WJ Zhang, Diamond nanostructures for drug delivery, bioimaging, and biosensing, Chemical Society Reviews, 46, 734-760, 2017.
  2. L Yan, MJ Zhou, XJ Zhang, LB Huang, W Chen, VAL Roy, WJ Zhang, X Chen, A novel type of aqueous dispersible ultrathin layered double hydroxide nanosheets for in vivo bioimaging and drug delivery, ACS Applied Materials & Interfaces, 9(39), 34185-34193, 2017.
  3. JF Zhang, YN Li, FF An, XH Zhang, X Chen, CS Lee, Preparation and size control of sub-100 nm pure nanodrugs, Nano Letters, 15(1), 313-318, 2015.
  4. L Yan, JF Zhang, CS Lee, X Chen, Micro- and nanotechnologies for intracellular delivery, Small, 10(22), 4487-4504, 2014.
  5. L Yan, W Chen, XY Zhu, LB Huang, ZG Wang, GY Zhu, VAL Roy, KN Yu, X Chen, Folic acid conjugated self-assembled layered double hydroxides nanoparticles for high-efficacy-targeted drug delivery, Chemical Communications, 49, 10938-10940, 2013.

Closing Date: 

Wednesday, February 21, 2018
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School of Engineering, University of Edinburgh

Principal Supervisor: 

Eligibility: 

Minimum entry qualification - an Honours degree at 2:1 or above (or International equivalent) in chemical engineering, chemistry, materials science, biomedical engineering or cell biology, possibly supported by an MSc Degree.

Further information on English language requirements for EU/Overseas applicants.

Funding: 

EPSRC funding is available to cover tuition fees and stipend are available for Home/EU students, but applications are also welcomed from self-funded students, or students who are applying for scholarships from the University of Edinburgh or elsewhere.

Further information and other funding options.

Informal Enquiries: