The burgeoning field of synthetic biology offers promising avenues for engineering artificial cells with tailored functionalities for diverse biomedical applications. This PhD project aims to explore novel strategies for designing and constructing synthetic cells capable of performing complex tasks, mimicking natural cellular behaviors, and interfacing with biological systems.
The objectives of the project include: (1) Develop innovative methodologies for constructing synthetic cells with membrane architectures, and intracellular machinery; (2) Investigate strategies for incorporating biomimetic features into synthetic cells, including cellular compartments, membrane proteins, and signaling pathways; (3) Characterize the biophysical properties and functional capabilities of synthetic cells; (4) Explore the potential applications of synthetic cells in drug delivery, biosensing, regenerative medicine, or tissue engineering; and (5) Evaluate the biocompatibility, stability, and safety profiles of synthetic cells in vitro and in vivo.
Further Information:
https://xianfengchen.wixsite.com/biomaterials
The University of Edinburgh is committed to equality of opportunity for all its staff and students, and promotes a culture of inclusivity. Please see details here: https://www.ed.ac.uk/equality-diversity
Closing Date:
Principal Supervisor:
Eligibility:
Entry requirement: minimum entry qualification – an Honours degree at 2:1 or above (or international equivalent) in chemical engineering, chemistry, materials science, biomedical engineering, or cell biology. English language requirements need to be satisfied by EU/Overseas applicants.
Minimum entry qualification - an Honours degree at 2:1 or above (or International equivalent) in a relevant science or engineering discipline, possibly supported by an MSc Degree. Further information on English language requirements for EU/Overseas applicants.
Funding:
Applications are welcomed from self-funded students, or students who are applying for scholarships from the University of Edinburgh or elsewhere
