Dr Michael Xianfeng Chen

Personal Chair of Therapeutic Engineering

Telephone

+44(0)131 6502784

Location

2.069 Faraday Building

Engineering Discipline

Chemical Engineering

Research Institutes

Bioengineering
Research Publications
Prof Michael Chen

Prof. Chen’s research is focused on biomaterials, biomedical engineering, biophysics, and the application of nanomaterials in biology and medicine. In these areas, he has been working on physical (microneedle & nanoneedle arrays) and chemical (nanomaterials) for drug delivery and sensing, as well as microfluidic devices for biomedical applications.

He has published >130 papers in peer-reviewed journals including Nature Communications, Advanced Materials, Angewandte Chemie International Edition, Advanced Functional Materials, Small, Advanced Healthcare Materials, Journal of the American Chemical Society, Nano Letters, ACS Nano, Biomaterials, Journal of Controlled Release, Advanced Drug Delivery Reviews, and Chemical Society Reviews. These publications generated an h-index of 58 and >9000 citations. Additionally, he has 3 book chapters and 12 granted patents & 15 patent applications in drug delivery technologies in major countries and regions, mostly in the USA and Europe. His research output has attracted broad media coverage including TV, newspapers, internet websites, journal cover, and journal cover stories.​

His research has been supported by grants from MRC (nanomedicine), ESRC (sing-cell analysis), EPSRC (Phase 0 clinical trial tool development), industry (hydrogel, nanomedicine, antibacterial coatings), Cancer Research UK (biosensor), Royal Society (microfluidic nanomedicine synthesis), and Royal Society of Edinburgh (nanomedicine, biosensor), etc.

Examples of his contribution to technology include: 1. Microneedle transdermal delivery: Invented technology for coating vaccines on small and densely packed microneedles for efficient skin vaccination (22 patents and >20 journal papers); this technology contributed to the establishment of Vaxxas (https://www.vaxxas.com/about-vaxxas/);  2. Diamond nanoneedle arrays: Pioneered diamond nanoneedle arrays for high-throughput intracellular delivery (3 patents and >10 journal papers); 3. Programmable Optical Window Bonding: Invented this technology enabling high-resolution, transparent microfluidic device production through 3D printing.

For scientific community service, he serves as a reviewer for many fields' top journals such as Science Robotics, Nature Communications, Science Advances, Advanced Materials, Small, Advanced Healthcare Materials, Journal of the American Chemical Society, ACS Nano, Nano Letters, ACS Applied Materials & Interfaces, Journal of Controlled Release, Biomaterials, Advanced Drug Delivery Reviews, and grant proposals from different research councils in the UK (e.g., EPSRC, BBSRC, MRC, CRUK, and Royal Society) and a number of other countries. He is also an associate editor of IET Nanobiotechnology and an editorial board member of Sensors, Bioengineering, and Journal of Functional Biomaterials.

  • DPhil in Materials Science, University of Oxford
  • MSc in Chemistry, National University of Singapore

  • Fellow of the Higher Education Academy (HEA), United Kingdom
  • Member of the Royal Society of Chemistry (RSC), United Kingdom

  • Process Plant Engineering CHEE08016
  • Nanomaterials in Chemical & Biomedical Engineering CHEE11026 (With Dr Norbert Radacsi)

  • Advanced drug delivery systems
  • Antibacterial
  • Biodegradable nanomedicine
  • Biomaterials
  • Biomedical imaging
  • Biosensing
  • Cancer therapy and diagnosis
  • Hydrogel
  • Microfluidics
  • Nanomaterials and nanotechnology
  • Nanotoxicology

We welcome outstanding PhD applicants to join our group to perform research in bioengineering, biomaterials, and the application of nanomaterials in biology, medicine, and healthcare. Except the research group funding, the following scholarships can be applied to support your study. These are just a few examples, rather than the full list. The School of Engineering also provides PhD scholarships for exceptional applicants.

Currently, we have an EPSRC/MRC CDT scholarship for urgent application (Project 2: Imaging tumour macrophage polarisation for non-invasive evaluation of anticancer therapy). The applicants must be UK citizens or EU citizens who have been living in the UK for a minimum of 3 years. The deadline is 26/07/2018.

Edinburgh Global Research Scholarship

These awards are designed to attract high quality overseas research students to the University of Edinburgh.

http://www.ed.ac.uk/student-funding/postgraduate/international/global/research

Principal's Career Development PhD Scholarships

http://www.ed.ac.uk/student-funding/postgraduate/international/other-funding/development

China Scholarships Council/University of Edinburgh Scholarships (Citizens and permanent residents of the People's Republic of China)

Croucher Foundation Study awards (Permanent Hong Kong residents)

Postdoctoral researchers are welcome to join the group to perform research in bioengineering, biomaterials, and the application of nanomaterials in biology, medicine, environment and energy. Outstanding applicants can consider the following fellowship (just a few examples).

Newton International Fellowships

Marie Skłodowska-Curie Fellowships

Sir Henry Wellcome Postdoctoral Fellowships