Applications are invited for a postgraduate research opportunity leading to a PhD in Biomedical Engineering, focused on a materials-based approach to enhance chronic wound healing outcomes.This project will be conducted within a collaborative research setting, utilizing cutting-edge laboratories for materials characterization and biological testing at Heriot-Watt University (led by Professor Michael Crichton) and The University of Edinburgh (with Dr. Anthony Callanan). Additionally, you will collaborate with Dr. Jenna Cash’s cutaneous immunology and wound healing lab at the Institute of Repair and Regeneration at the University of Edinburgh.Tissue regeneration holds significant promise for treating and understanding various degenerative conditions, such as osteoarthritis and cardiovascular disease, by designing biological scaffolds using synthetic biodegradable polyesters and natural extracellular matrix materials. This research aims to develop synthetic-based tissue-regenerative scaffolds to advance treatments for chronic wounds.The research will employ electrospinning to fabricate dressings from polymers like polycaprolactone (PCL) and collagen, tailored to mimic the diverse collagen-structure profiles found at different life stages. Targeting molecules will be incorporated to enhance functionality. The focus will be on refining release profiles to ensure sustained and controlled delivery, boosting therapeutic efficacy. In vitro evaluations will assess performance, followed by collaborative functional assessments.The student will develop skills in biomaterial design, fabrication, characterization, and cell culture, using techniques such as scanning electron microscopy, nano-indentation, mechanical property testing, ELISA, and real-time RT-PCR. These skills are crucial for pursuing careers in the biomedical sector or academia, particularly in Tissue Engineering and Biomedical Engineering. Further information Dr. Anthony Callanan - Google Scholar ProfileProfessor Michael Crichton - Google Scholar ProfileDr. Jenna Cash - Edinburgh University ProfileDr. Jenna Cash - Google Scholar Profile Closing date: 27 Jan, 2026 Apply now Principal Supervisor Dr Anthony Callanan Assistant Supervisor Professor Michael Crichton Eligibility To undertake this research, we are seeking a motivated candidate with an honors degree at 2:1 or above in any of these areas, chemical engineering, chemistry, materials science, physics, mechanical engineering, biomedical engineering, synthetic chemistry, organic chemistry, biochemistry, molecular biology or a related discipline. Funding Competition funding opportunities available through the Edinburgh Research Partnership in Engineering (ERPE) Joint PhD Studentships – please enquireApplications are welcomed from self-funded students, or students who are applying for scholarships from the University of Edinburgh or elsewhereFurther information and other funding options.
