Are you interested in pursuing a PhD at the interface of chemical engineering, materials science, and microbiology at the University of Edinburgh? We are seeking a talented, motivated, and curious PhD student to develop innovative strategies for the safe and sustainable reprocessing of reusable medical devices. Reusable medical devices are central to modern healthcare. Their use reduces costs for healthcare systems such as the NHS and minimises environmental impact compared to single-use alternatives. However, their safe reuse depends critically on effective decontamination. While cleaning removes visible contamination, disinfection targets microscopic pathogens from previous patients. These microorganisms often exist as complex, highly resistant biofilm communities that are difficult to eradicate. Current reprocessing methods rely on aggressive physical and chemical treatments, which can unintentionally damage device surfaces. This can lead to microplastic release, as well as the formation of microcracks and surface grooves that promote further bacterial adhesion and resistance. This project addresses a key challenge: How can we effectively disinfect reusable medical devices without degrading materials or promoting microbial attachment? You will work with a custom-built laboratory system to simulate decontamination processes in a controlled manner. This will enable you to: Investigate how different cleaning conditions influence surface degradation and microplastic releaseGrow and analyse biofilms on treated surfaces using advanced microscopy techniquesExplore whether engineered surface patterns can reduce microbial attachmentDevelop and test surface functionalisation strategies to inhibit biofilm formation This interdisciplinary project combines experimentation, surface engineering, and microbiological analysis. You will also collaborate with leading UK medical device reprocessing companies, ensuring strong real-world impact. As a PhD student, you will benefit from a dynamic research environment and opportunities to present your work at conferences, workshops, and seminars, while building both academic and industry collaborations. EligibilityAn excellent undergraduate degree (at least a UK 2:1 honours degree, or international equivalent) in Chemical Engineering, Materials Science, Biomedical Engineering, or a related fieldA Master’s degree (MSc/MEng) in a relevant discipline is desirable Interest in surface science, interfacial engineering, microbiology, and laboratory-based research Strong analytical and problem-solving skills Experience with microscopy techniques (SEM, TEM, AFM) is advantageous Closing Date 22nd September 2026 Please note that the position may be filled before the closing date if a suitable candidate is identified. Funding This project is currently open to self-funded applicants. You will be embedded within a highly supportive and well-resourced research environment at the University of Edinburgh, with access to state-of-the-art laboratory facilities. Exceptional candidates will also be supported in applying for competitive external funding opportunities, scholarships, and sponsorships as they arise. Application Documents Curriculum VitaeDegree Transcripts and CertificatesResearch Proposal (not more than 3 pages) Further information For informal enquiries, please contact: eepelle@ed.ac.uk The University of Edinburgh is committed to equality, diversity, and inclusion, and welcomes applications from all qualified candidates.Ozone Decontamination of Medical and Nonmedical Devices: An Assessment of Design and Implementation Considerations: (https://doi.org/10.1021/acs.iecr.2c03754) Efficacy of gaseous ozone and UVC radiation against Candida auris biofilms on polystyrene surfaces (https://doi.org/10.1016/j.jece.2024.113862) Closing date:  22 Sep, 2026 Apply now Principal Supervisor Dr Emmanuel Epelle Assistant Supervisor Dr Santiago Romero-Vargas Castrillon Eligibility An excellent undergraduate degree (at least a UK 2:1 honours degree, or international equivalent) in Chemical Engineering, Materials Science, Biomedical Engineering, or a related fieldA Master’s degree (MSc/MEng) in a relevant discipline is desirableInterest in surface science, interfacial engineering, microbiology, and laboratory-based researchStrong analytical and problem-solving skillsExperience with microscopy techniques (SEM, TEM, AFM) is advantageous Funding This project is currently open to self-funded applicants. You will be embedded within a highly supportive and well-resourced research environment at the University of Edinburgh, with access to state-of-the-art laboratory facilities. Exceptional candidates will also be supported in applying for competitive external funding opportunities, scholarships, and sponsorships as they arise.Further information and other funding options. Informal Enquiries eepelle@ed.ac.uk